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OCR: paratus Although development of the sexual a generated depends on the hormonal environmer s of male by the developing testis, the earliest sig gonad is differentiation can be detected before th biting morphologically distinct. Mullerian in the factor (MIF), a glycoprotein elaborated niferous developing Sertoli cells within the sen an ducts tubules, causes regression of the Mulle which would otherwise follow a fema. differentiation pathway, See later: . Male Differentiation and DHT